Safety and efficacy of interferon γ in friedreich's ataxia.

Vavla M, D'Angelo MG, Arrigoni F, Toschi N, Peruzzo D, Gandossini S, Russo A, Diella E, Tirelli S, Salati R, Scarpazza P, Luffarelli R, Fortuni S, Rufini A, Condò I, Testi R, Martinuzzi A.

Mov Disord. 2020 Feb;35(2):370-371.

Frataxin deficiency in Friedreich's ataxia is associated with reduced levels of HAX-1, a regulator of cardiomyocyte death and survival.

Tiano F, Amati F, Cherubini F, Morini E, Vancheri C, Maletta S, Fortuni S, Serio D, Quatrana A, Luffarelli R, Benini M, Alfedi G, Panarello L, Rufini A, Toschi N, Frontali M, Romano S, Marcotulli C, Casali C, Gioiosa S, Mariotti C, Mongelli A, Fichera M, Condò I, Novelli G, Testi R, Malisan F.

Hum Mol Genet. 2020 Feb 1;29(3):471-482.

SINEUP non-coding RNAs rescue defective frataxin expression and activity in a cellular model of Friedreich's Ataxia.

Bon C, Luffarelli R, Russo R, Fortuni S, Pierattini B, Santulli C, Fimiani C, Persichetti F, Cotella D, Mallamaci A, Santoro C, Carninci P, Espinoza S, Testi R, Zucchelli S, Condò I, Gustincich S.

Nucleic Acids Res. 2019 Nov 18;47(20):10728-10743.

Drug repositioning screening identifies etravirine as a potential therapeutic for friedreich's ataxia.

Alfedi G, Luffarelli R, Condò I, Pedini G, Mannucci L, Massaro DS, Benini M, Toschi N, Alaimo G, Panarello L, Pacini L, Fortuni S, Serio D, Malisan F, Testi R, Rufini A.

Mov Disord. 2019 Mar;34(3):323-334.

Biophysical characterisation of the recombinant human frataxin precursor.

Castro IH, Ferrari A, Herrera MG, Noguera ME, Maso L, Benini M, Rufini A, Testi R, Costantini P, Santos J.

FEBS Open Bio. 2018 Jan 25;8(3):390-405.

E3 Ligase RNF126 Directly Ubiquitinates Frataxin, Promoting Its Degradation: Identification of a Potential Therapeutic Target for Friedreich Ataxia.

Benini M, Fortuni S, Condò I, Alfedi G, Malisan F, Toschi N, Serio D, Massaro DS, Arcuri G, Testi R, Rufini A.

Cell Rep. 2017 Feb 21;18(8):2007-2017.

Analyzing the Effects of a G137V Mutation in the FXN Gene.

Faggianelli N, Puglisi R, Veneziano L, Romano S, Frontali M, Vannocci T, Fortuni S, Testi R, Pastore A.

Front Mol Neurosci. 2015 Nov 25;8:66.

GIFT-1, a phase IIa clinical trial to test the safety and efficacy of IFNγ administration in FRDA patients. Marcotulli C, Fortuni S, Arcuri G, Tomassini B, Leonardi L, Pierelli F, Testi R, Casali C.

Neurol Sci. 2015 Nov 30. [Epub ahead of print]

Src inhibitors modulate frataxin protein levels.

Cherubini F, Serio D, Guccini I, Fortuni S, Arcuri G, Condò I, Rufini A, Moiz S, Camerini S, Crescenzi M, Testi R, Malisan F.

Hum Mol Genet. 2015 Aug 1;24(15):4296-305. doi: 10.1093/hmg/ddv162. Epub 2015 May 6.

Highly specific ubiquitin-competing molecules effectively promote frataxin accumulation and partially rescue the aconitase defect in Friedreich ataxia cells.

Rufini A, Cavallo F, Condò I, Fortuni S, De Martino G, Incani O, Di Venere A, Benini M, Massaro DS, Arcuri G, Serio D, Malisan F, Testi R.

Neurobiol Dis. 2015 Mar;75:91-9. doi: 10.1016/j.nbd.2014.12.011. Epub 2014 Dec 27.

Autophagy induction extends lifespan and reduces lipid content in response to frataxin silencing in C. elegans.

Schiavi A, Torgovnick A, Kell A, Megalou E, Castelein N, Guccini I, Marzocchella L, Gelino S, Hansen M, Malisan F, Condò I, Bei R, Rea SL, Braeckman BP, Tavernarakis N, Testi R, Ventura N.

Exp Gerontol. 2013 Feb;48(2):191-201. doi: 10.1016/j.exger.2012.12.002. Epub 2012 Dec 13.

Interferon gamma upregulates frataxin and corrects the functional deficits in a Friedreich ataxia model.

Tomassini B, Arcuri G, Fortuni S, Sandi C, Ezzatizadeh V, Casali C, Condò I, Malisan F, Al-Mahdawi S, Pook M, Testi R.

Hum Mol Genet. 2012 Jul 1;21(13):2855-61. doi: 10.1093/hmg/dds110. Epub 2012 Mar 23.

Frataxin participates to the hypoxia-induced response in tumors.

Guccini I, Serio D, Condò I, Rufini A, Tomassini B, Mangiola A, Maira G, Anile C, Fina D, Pallone F, Mongiardi MP, Levi A, Ventura N, Testi R, Malisan F.

Cell Death Dis. 2011 Feb 24;2(1):e123.

Preventing the ubiquitin-proteasome-dependent degradation of frataxin, the protein defective in Friedreich's ataxia.

Rufini A, Fortuni S, Arcuri G, Condò I, Serio D, Incani O, Malisan F, Ventura N, Testi R.

Hum Mol Genet. 2011 Jan 19. [Epub ahead of print]

A role for p53 in mitochondrial stress response control of longevity in C. elegans.

Torgovnick A, Schiavi A, Testi R, Ventura N.

Exp Gerontol. 2010 Aug;45(7-8):550-7. Epub 2010 Feb 19

Molecular control of the cytosolic aconitase/IRP1 switch by extramitochondrial frataxin.

Condò I, Malisan F, Guccini I, Serio D, Rufini A, Testi R.

Hum Mol Genet. 2010 Apr 1;19(7):1221-9. Epub 2010 Jan 6.

p53/CEP-1 increases or decreases lifespan, depending on level of mitochondrial bioenergetic stress.

Ventura N, Rea SL, Schiavi A, Torgovnick A, Testi R, Johnson TE.

Aging Cell. 2009 Aug;8(4):380-93. Epub 2009 Apr 22.

ATM kinase activity modulates Fas sensitivity through the regulation of FLIP in lymphoid cells.

Stagni V, di Bari MG, Cursi S, Condò I, Cencioni MT, Testi R, Lerenthal Y, Cundari E, Barilà D.

Blood. 2008 Jan 15;111(2):829-37. Epub 2007 Oct 11.

In vivo maturation of human frataxin.

Condò I, Ventura N, Malisan F, Rufini A, Tomassini B, Testi R.

Hum Mol Genet. 2007 Jul 1;16(13):1534-40. Epub 2007 Apr 27.

Long-lived C. elegans mitochondrial mutants as a model for human mitochondrial-associated diseases.

Ventura N, Rea SL, Testi R.

Exp Gerontol. 2006 Oct;41(10):974-91. Epub 2006 Sep 1. Review.

5-aminosalicylic acid enhances anchorage-independent colorectal cancer cell death.

Fina D, Franchi L, Caruso R, Peluso I, Naccari GC, Bellinvia S, Testi R, Pallone F, Monteleone G.

Eur J Cancer. 2006 Oct;42(15):2609-16. Epub 2006 Aug 17.

C. elegans as a model for Friedreich Ataxia.

Ventura N, Rea SL, Handerson ST, Condò I, Testi R, Johnson TE.

FASEB J. 2006 May;20(7):1029-30. No abstract available.

c-Abl acetylation by histone acetyltransferases regulates its nuclear-cytoplasmic localization.

di Bari MG, Ciuffini L, Mingardi M, Testi R, Soddu S, Barilà D.

EMBO Rep. 2006 Jul;7(7):727-33. Epub 2006 Apr 28.

Src kinase phosphorylates Caspase-8 on Tyr380: a novel mechanism of apoptosis suppression. (130 citations)

Cursi S, Rufini A, Stagni V, Condò I, Matafora V, Bachi A, Bonifazi AP, Coppola L, Superti-Furga G, Testi R, Barilà D.

EMBO J. 2006 May 3;25(9):1895-905. Epub 2006 Apr 13.

A pool of extramitochondrial frataxin that promotes cell survival.

Condò I, Ventura N, Malisan F, Tomassini B, Testi R.

J Biol Chem. 2006 Jun 16;281(24):16750-6. Epub 2006 Apr 11.

9-O-acetyl GD3 protects tumor cells from apoptosis.

Kniep B, Kniep E, Ozkucur N, Barz S, Bachmann M, Malisan F, Testi R, Rieber EP.

Int J Cancer. 2006 Jul 1;119(1):67-73.

Ceramide catabolism critically controls survival of human dendritic cells.

Franchi L, Malisan F, Tomassini B, Testi R.

J Leukoc Biol. 2006 Jan;79(1):166-72. Epub 2005 Oct 21.

Silencing of SH-PTP2 defines a crucial role in the inactivation of epidermal growth factor receptor by 5-aminosalicylic acid in colon cancer cells.

Monteleone G, Franchi L, Fina D, Caruso R, Vavassori P, Monteleone I, Calabrese E, Naccari GC, Bellinvia S, Testi R, Pallone F.

Cell Death Differ. 2006 Feb;13(2):202-11.

The ganglioside GD3 as the Greek goddess Hecate: several faces turned towards as many directions.

Malisan F, Testi R.

IUBMB Life. 2005 Jul;57(7):477-82. Review.

Reduced expression of frataxin extends the lifespan of Caenorhabditis elegans.

Ventura N, Rea S, Henderson ST, Condo I, Johnson TE, Testi R.

Aging Cell. 2005 Apr;4(2):109-12.

Differential regulation of apoptotic cell death in senescent human cells.

Hampel B, Malisan F, Niederegger H, Testi R, Jansen-Dürr P.

Exp Gerontol. 2004 Nov-Dec;39(11-12):1713-21.

Calnexin suppresses GD3 synthase-induced apoptosis.

Tomassini B, Malisan F, Franchi L, Nicolò C, Calvo GB, Saito T, Testi R.

FASEB J. 2004 Oct;18(13):1553-5. Epub 2004 Aug 19.

p21(Waf1/Cip1/Sdi1) mediates shear stress-dependent antiapoptotic function.

Mattiussi S, Turrini P, Testolin L, Martelli F, Zaccagnini G, Mangoni A, Barlucchi LM, Antonini A, Illi B, Cirielli C, Padron J, Nicolò C, Testi R, Osculati F, Biglioli P, Capogrossi MC, Gaetano C.

Cardiovasc Res. 2004 Mar 1;61(4):693-704.

Analysis of intracellular distribution and apoptosis involvement of the Ufd1l gene product by over-expression studies.

Amati F, Condò I, Conti E, Sangiuolo F, Dallapiccola B, Testi R, Novelli G.

Cell Biochem Funct. 2003 Sep;21(3):263-7.

Mitochondrial lipids as apoptosis regulators.

Malisan F, Testi R.

Curr Med Chem. 2003 Aug;10(16):1573-80. Review.

A caspaselike activity is triggered by LPS and is required for survival of human dendritic cells.

Franchi L, Condò I, Tomassini B, Nicolò C, Testi R.

Blood. 2003 Oct 15;102(8):2910-5. Epub 2003 Jun 26.

Caspase-dependent cleavage of c-Abl contributes to apoptosis.

Barilà D, Rufini A, Condò I, Ventura N, Dorey K, Superti-Furga G, Testi R.

Mol Cell Biol. 2003 Apr;23(8):2790-9.

GD3 ganglioside and apoptosis.

Malisan F, Testi R. (100 citations)

Biochim Biophys Acta. 2002 Dec 30;1585(2-3):179-87. Review.

Is it cytotoxicity or apoptosis which causes cell death in autoimmunity?

Franchi L, Testi R.

Springer Semin Immunopathol. 2002 Dec;24(3):331-41. Review. No abstract available.

Acetylation suppresses the proapoptotic activity of GD3 ganglioside.

Malisan F, Franchi L, Tomassini B, Ventura N, Condò I, Rippo MR, Rufini A, Liberati L, Nachtigall C, Kniep B, Testi R.

J Exp Med. 2002 Dec 16;196(12):1535-41.

GD3 in cellular ageing and apoptosis.

Malisan F, Testi R.

Exp Gerontol. 2002 Oct-Nov;37(10-11):1273-82. Review.

Disialoganglioside GD3 is released by microglia and induces oligodendrocyte apoptosis.

Simon BM, Malisan F, Testi R, Nicotera P, Leist M.

Cell Death Differ. 2002 Jul;9(7):758-67.

Lipid signaling in CD95-mediated apoptosis.

Rufini A, Testi R.

Subcell Biochem. 2002;36:285-308. Review. No abstract available.

Mitochondria as sensors of sphingolipids.

Tomassini B, Testi R.

Biochimie. 2002 Feb-Mar;84(2-3):123-9. Review.

UVB-induced apoptosis of human dendritic cells: contribution by caspase-dependent and caspase-independent pathways.

Nicolò C, Tomassini B, Rippo MR, Testi R.

Blood. 2001 Mar 15;97(6):1803-8.

GD3 ganglioside as an intracellular mediator of apoptosis.

Rippo MR, Malisan F, Ravagnan L, Tomassini B, Condò I, Costantini P, Susin SA, Rufini A, Todaro M, Kroemer G, Testi R.

Eur Cytokine Netw. 2000 Sep;11(3):487-8. No abstract available.

Intracellular mediators of programmed cell death initiated at the cell surface receptor Fas.

Condo I, Testi R.

Transpl Int. 2000;13 Suppl 1:S3-6. Review.

GD3 ganglioside directly targets mitochondria in a bcl-2-controlled fashion.

Rippo MR, Malisan F, Ravagnan L, Tomassini B, Condo I, Costantini P, Susin SA, Rufini A, Todaro M, Kroemer G, Testi R.

FASEB J. 2000 Oct;14(13):2047-54. (170 citations)

Lipopolysaccharide induces jun N-terminal kinase activation in macrophages by a novel Cdc42/Rac-independent pathway involving sequential activation of protein kinase C zeta and phosphatidylcholine-dependent phospholipase C.

Procyk KJ, Rippo MR, Testi R, Hofmann F, Parker PJ, Baccarini M.

Blood. 2000 Oct 1;96(7):2592-8.

Primary macrophages infected by human immunodeficiency virus trigger CD95-mediated apoptosis of uninfected astrocytes.

Aquaro S, Panti S, Caroleo MC, Balestra E, Cenci A, Forbici F, Ippolito G, Mastino A, Testi R, Mollace V, Caliò R, Perno CF.

J Leukoc Biol. 2000 Sep;68(3):429-35.

Distinct mechanisms target stress and extracellular signal-activated kinase 1 and Jun N-terminal kinase during infection of macrophages with Salmonella.

Procyk KJ, Rippo MR, Testi R, Hoffmann F, Parker PJ, Baccarini M.

J Immunol. 1999 Nov 1;163(9):4924-30.

Lipid signaling in CD95-mediated apoptosis.

Malisan F, Testi R.

FEBS Lett. 1999 Jun 4;452(1-2):100-3. Review.

Lipid and glycolipid mediators in CD95-induced apoptotic signaling.

Malisan F, Rippo MR, De Maria R, Testi R.

Results Probl Cell Differ. 1999;23:65-76. Review. No abstract available.

Fas/Fas ligand-driven T cell apoptosis as a consequence of ineffective thyroid immunoprivilege in Hashimoto's thyroiditis.

Stassi G, Todaro M, Bucchieri F, Stoppacciaro A, Farina F, Zummo G, Testi R, De Maria R.

J Immunol. 1999 Jan 1;162(1):263-7.

Caspases mediate retinoic acid-induced degradation of the acute promyelocytic leukemia PML/RARalpha fusion protein.

Nervi C, Ferrara FF, Fanelli M, Rippo MR, Tomassini B, Ferrucci PF, Ruthardt M, Gelmetti V, Gambacorti-Passerini C, Diverio D, Grignani F, Pelicci PG, Testi R.

Blood. 1998 Oct 1;92(7):2244-51. (170 citations)

Fas-FasL interactions: a common pathogenetic mechanism in organ-specific autoimmunity.

De Maria R, Testi R.

Immunol Today. 1998 Mar;19(3):121-5. Review. (150 citations)

Acidic sphingomyelinase (ASM) is necessary for fas-induced GD3 ganglioside accumulation and efficient apoptosis of lymphoid cells.

De Maria R, Rippo MR, Schuchman EH, Testi R.

J Exp Med. 1998 Mar 16;187(6):897-902. (160 citations)

CD95 and CD95-ligand expression in endocrine pancreas of NOD, NOR and BALB/c mice.

Signore A, Annovazzi A, Procaccini E, Beales PE, Spencer J, Testi R, Ruberti G.

Diabetologia. 1997 Dec;40(12):1476-9.

Nitric oxide primes pancreatic beta cells for Fas-mediated destruction in insulin-dependent diabetes mellitus.

Stassi G, De Maria R, Trucco G, Rudert W, Testi R, Galluzzo A, Giordano C, Trucco M.

J Exp Med. 1997 Oct 20;186(8):1193-200. (280 citations)

Requirement for GD3 ganglioside in CD95- and ceramide-induced apoptosis.

De Maria R, Lenti L, Malisan F, d'Agostino F, Tomassini B, Zeuner A, Rippo MR, Testi R.

Science. 1997 Sep 12;277(5332):1652-5. Erratum in: Science 1998 Apr 17;280(5362):363. (410 citations)

The interaction of sperm cells with exogenous DNA: a role of CD4 and major histocompatibility complex class II molecules.

Lavitrano M, Maione B, Forte E, Francolini M, Sperandio S, Testi R, Spadafora C.

Exp Cell Res. 1997 May 25;233(1):56-62. (100 citations)

Fas-induced changes in cdc2 and cdk2 kinase activity are not sufficient for triggering apoptosis in HUT-78 cells.

De Luca A, De Maria R, Baldi A, Trotta R, Facchiano F, Giordano A, Testi R, Condorelli G.

J Cell Biochem. 1997 Mar 15;64(4):579-85.

Potential involvement of Fas and its ligand in the pathogenesis of Hashimoto's thyroiditis.

Giordano C, Stassi G, De Maria R, Todaro M, Richiusa P, Papoff G, Ruberti G, Bagnasco M, Testi R, Galluzzo A.

Science. 1997 Feb 14;275(5302):960-3. (640 citations)

Sphingomyelin breakdown and cell fate.

Testi R.

Trends Biochem Sci. 1996 Dec;21(12):468-71. Review. (220 citations)

Ceramide inhibits antigen uptake and presentation by dendritic cells.

Sallusto F, Nicolò C, De Maria R, Corinti S, Testi R.

J Exp Med. 1996 Dec 1;184(6):2411-6.

Stimulated human lamina propria T cells manifest enhanced Fas-mediated apoptosis.

Boirivant M, Pica R, DeMaria R, Testi R, Pallone F, Strober W.

J Clin Invest. 1996 Dec 1;98(11):2616-22. (140 citations)

Cell-associated ceramide in HIV-1-infected subjects.

De Simone C, Cifone MG, Alesse E, Steinberg SM, Di Marzio L, Moretti S, Famularo G, Boschini A, Testi R.

AIDS. 1996 Jun;10(6):675-6. No abstract available.

Educational Corner: Ceramide-mediated pathways in FAS/APO-1 signalling.

Testi R.

Cell Death Differ. 1996 Apr;3(2):246. No abstract available.

Functional expression of Fas and Fas ligand on human gut lamina propria T lymphocytes. A potential role for the acidic sphingomyelinase pathway in normal immunoregulation.

De Maria R, Boirivant M, Cifone MG, Roncaioli P, Hahne M, Tschopp J, Pallone F, Santoni A, Testi R.

J Clin Invest. 1996 Jan 15;97(2):316-22. (130 citations)

Ceramide, AIDS and long-term survivors.

De Simone C, Grazia Cifone M, Roncaioli P, Moretti S, Famularo G, Alesse E, Boschini A, Testi R.

Immunol Today. 1996 Jan;17(1):48. No abstract available.

Fas/Apo-1 (CD95) receptor lacking the intracytoplasmic signaling domain protects tumor cells from Fas-mediated apoptosis.

Cascino I, Papoff G, De Maria R, Testi R, Ruberti G.

J Immunol. 1996 Jan 1;156(1):13-7. (190 citations)

Multiple pathways originate at the Fas/APO-1 (CD95) receptor: sequential involvement of phosphatidylcholine-specific phospholipase C and acidic sphingomyelinase in the propagation of the apoptotic signal.

Cifone MG, Roncaioli P, De Maria R, Camarda G, Santoni A, Ruberti G, Testi R.

EMBO J. 1995 Dec 1;14(23):5859-68. (310 citations)

Defective expression of the apoptosis-inducing CD95 (Fas/APO-1) molecule on T and B cells in IDDM.

Giordano C, De Maria R, Stassi G, Todaro M, Richiusa P, Giordano M, Testi R, Galluzzo A.

Diabetologia. 1995 Dec;38(12):1449-54.

Role of CD69 in NO production by human monocytes.

Testi R, Cifone MG, Santoni A.

Res Immunol. 1995 Nov-Dec;146(9):682-3. Review. No abstract available.

Diacylglycerol lipase activation and 5-lipoxygenase activation and translocation following TCR/CD3 triggering in T cells.

Cifone MG, Cironi L, Santoni A, Testi R.

Eur J Immunol. 1995 Apr;25(4):1080-6.

Persistent in vivo activation and transient anergy to TCR/CD3 stimulation of normal human intestinal lymphocytes.

DeMaria R, Fais S, Testi R.

Adv Exp Med Biol. 1995;371A:43-6. No abstract available.

Triggering of human monocyte activation through CD69, a member of the natural killer cell gene complex family of signal transducing receptors.

De Maria R, Cifone MG, Trotta R, Rippo MR, Festuccia C, Santoni A, Testi R.

J Exp Med. 1994 Nov 1;180(5):1999-2004. (160 citations)

The CD69 receptor: a multipurpose cell-surface trigger for hematopoietic cells.

Testi R, D'Ambrosio D, De Maria R, Santoni A.

Immunol Today. 1994 Oct;15(10):479-83. Review. (470 citations)

Apoptotic signaling through CD95 (Fas/Apo-1) activates an acidic sphingomyelinase.

Cifone MG, De Maria R, Roncaioli P, Rippo MR, Azuma M, Lanier LL, Santoni A, Testi R.

J Exp Med. 1994 Oct 1;180(4):1547-52. (620 citations)

Involvement of p21ras activation in T cell CD69 expression.

D'Ambrosio D, Cantrell DA, Frati L, Santoni A, Testi R.

Eur J Immunol. 1994 Mar;24(3):616-20. (150 citations)

Previous papers by R.Testi

A simple method for the evaluation of receptor binding capacity of modified cytokines.

Chianelli M, Signore A, Hicks R, Testi R, Negri M, Beverley PC.

J Immunol Methods. 1993 Dec 3;166(2):177-82.

Continuous in vivo activation and transient hyporesponsiveness to TcR/CD3 triggering of human gut lamina propria lymphocytes.

De Maria R, Fais S, Silvestri M, Frati L, Pallone F, Santoni A, Testi R.

Eur J Immunol. 1993 Dec;23(12):3104-8.

Transcriptional regulation of interleukin-2 gene expression by CD69-generated signals.

D'Ambrosio D, Trotta R, Vacca A, Frati L, Santoni A, Gulino A, Testi R.

Eur J Immunol. 1993 Nov;23(11):2993-7.

Preferential involvement of a phospholipase A2-dependent pathway in CD69-mediated platelet activation.

Testi R, Pulcinelli FM, Cifone MG, Botti D, Del Grosso E, Riondino S, Frati L, Gazzaniga PP, Santoni A.

J Immunol. 1992 May 1;148(9):2867-71.

CD69 is expressed on platelets and mediates platelet activation and aggregation.

Testi R, Pulcinelli F, Frati L, Gazzaniga PP, Santoni A.

J Exp Med. 1990 Sep 1;172(3):701-7.

Membrane anchoring of a human IgG Fc receptor (CD16) determined by a single amino acid.

Lanier LL, Cwirla S, Yu G, Testi R, Phillips JH.

Science. 1989 Dec 22;246(4937):1611-3.

CD3Ti+ human thymocyte-derived clones displaying a differential response to activation via CD3Ti and CD2.

Testi R, Alcover A, Spagnoli G, Reinherz EL, Acuto O.

Cell Immunol. 1989 Sep;122(2):350-64.

T cell activation via Leu-23 (CD69).

Testi R, Phillips JH, Lanier LL.

J Immunol. 1989 Aug 15;143(4):1123-8. (250 citations)

Laminin synthesis by NK cells and modulation of its expression by TPA (12-O-tetradecanoylphorbol-13-acetate).

Morrone S, Scarpa S, Punturieri A, Testi R, Gismondi A, Santoni G, Piccoli M, Frati L, Modesti A, Santoni A.

Exp Cell Res. 1989 Jun;182(2):543-9.

Identity of Leu-19 (CD56) leukocyte differentiation antigen and neural cell adhesion molecule.

Lanier LL, Testi R, Bindl J, Phillips JH.

J Exp Med. 1989 Jun 1;169(6):2233-8. (380 citations)

Membrane anchoring and spontaneous release of CD16 (FcR III) by natural killer cells and granulocytes.

Lanier LL, Phillips JH, Testi R.

Eur J Immunol. 1989 Apr;19(4):775-8.

Leu 23 induction as an early marker of functional CD3/T cell antigen receptor triggering. Requirement for receptor cross-linking, prolonged elevation of intracellular [Ca++] and stimulation of protein kinase C.

Testi R, Phillips JH, Lanier LL.

J Immunol. 1989 Mar 15;142(6):1854-60. (220 citations)

Functional expression of CD28 on T cell antigen receptor gamma/delta-bearing T lymphocytes.

Testi R, Lanier LL.

Eur J Immunol. 1989 Jan;19(1):185-8.

Structural and serological heterogeneity of gamma/delta T cell antigen receptor expression in thymus and peripheral blood.

Lanier LL, Ruitenberg J, Bolhuis RL, Borst J, Phillips JH, Testi R.

Eur J Immunol. 1988 Dec;18(12):1985-92.

Constitutive expression of a phosphorylated activation antigen (Leu 23) by CD3bright human thymocytes.

Testi R, Phillips JH, Lanier LL.

J Immunol. 1988 Oct 15;141(8):2557-63.

Proliferative effects of 12-O-tetradecanoylphorbol-13-acetate (TPA) and calcium ionophores on human large granular lymphocytes (LGL).

Procopio A, Gismondi A, Paolini R, Morrone S, Testi R, Piccoli M, Frati L, Herberman RB, Santoni A.

Cell Immunol. 1988 Apr 15;113(1):70-81.

Sequential metabolic events and morphological changes during in vivo large granular lymphocyte activation and proliferation.

Testi R, Galli MC, Piccoli M, Herberman RB, Frati L, Santoni A.

Cell Immunol. 1986 Oct 1;102(1):78-88.